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KMID : 0355220130380010035
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Journal of Korean Academy Oral Medicine
2013 Volume.38 No. 1 p.35 ~ p.51
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The Effect of Antioxidative Change in Cardiac Muscle of Obesity Rat by Treadmill Exercise with Intensity and Time
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Kim Myung-Hee
Kim Young-Eok
Yoon Chang-Lyuk
Ahn Jong-Mo
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Abstract
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The aims of this study was to observed an effect of antioxidative in cardiac muscle of high fat diet induced obesity rat by treadmill exercise with intensity and time. Thirty-two Sprauge-Dawley rats which were divided into four group. Normal, Control(high fat diet induced obesity rat), Experimental Ⅰ(high intensity intermittent exercise in high fat diet induced obesity rat), Experimental Ⅱ(moderate intensity endurance exercise in high fat diet induced obesity rat). The results of this study were as follows: 1. In change of body weight, the outcome of each group significantly difference compared with control. Also, 1 to 3 weeks significantly different compared with pre valu experimental Ⅰ and Ⅱ(p<0.001). 2. In change of lipid profile, the outcome of each group significantly difference compared with control(p<0.001). Difference between experimental Ⅰ and Ⅱ is not significantly. 3. In change of antioxidative enzymes(SOD, CAT, GPx) in myocardium, there are significant difference between control and experimental Ⅱ, and also between control and experimental Ⅰ(p<0.001). 4. In change of antioxidative protein MCR-1, the outcome of each group significantly difference compared with control(p<0.01). Experimental Ⅱ was most significantly difference than the other group(p<0.001). The above results suggest that treadmill exercise effectively reduced in fat. It would be considered that moderate intensity endurance exercise has an effects on improved antioxidative enzyme in cardiac muscle of high fat diet induced obesity rat.
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KEYWORD
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Antioxidative, Cardiac muscle, Obesity, Treadmill exercise
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